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Cesky Krumlov
ckrumlov.info

Places to Stay

 
Traveller's Hostel - http://www.travellers.cz

One of a million hostels in C.Krumlov. I stayed only one night because I couldn't stand the 'no curfew' rule. Drunk travellers wandered in as late/early as 4:30 in the morning. Dorm rooms hold about 10. Private/singles available. Downstairs/lobby is a fully staffed, fully stocked bar.
 
Things to Do
 
Click-sensitive map of Ceský Krumlov
 
Of all the places I went in the Czech Republic, it stands out in my mind the most. Not only is it beautiful, it has a wonderful atmosphere. They seem to have done a decent job regulating development--there are quite a lot of souvenir shops, but very few of the tacky T-shirt and coffee mug variety. Then again, I was there the first day it re-opened after the flood, so it wasn't very crowded. 
 
Don't miss the kanoo tour (bring six pack & sticky weed) and papa's restaurant, great steak! Trains are sort of a hassle, you get there with a local train from Budjovice (sp?) (=Budweis).

Day Trips

 
You might try Cesky Budejovice nearby. It's a bit larger and not quite so pretty, but it's also less touristed.